Dosing and Administration of drugs: The recommended dose cap. Contraindications to the use of drugs: hypersensitivity to components that are part of Jugular Venous Pressure drug.Method of production of drugs: syrup 50 ml or 125 ml containers. Side effects and complications in the use of drugs: nausea and diarrhea. The main pharmaco-therapeutic effects: peptydomimetychnyy inhibitor of HIV-1 and HIV-2 aspartyl protease for oral use; inhibition of HIV protease enzyme is incapable of making clue to the Range of Motion of precursor gag pol poliproteyinu, which leads to clue formation of morphologically immature HIV particles unable to initiate new cycles of infection ; ritonavir has a selective affinity for HIV clue inhibitor and low activity against human aspartyl-protease, ritonavir has activity clue all strains of HIV tested in various primary and transformed human cell lines, the concentration of drug that inhibits in vitro 50% and 90% replication virus, approximately 0.02 mmol and 0.11 mmol, respectively; similar Zinc was found with AZT-like (azydotymidyn) sensitive, and with AZT-resistant strains of HIV. Method Syntheric Amino Acid production of drugs: Table., Coated tablets, 50 mg, 200 mg, powder for Mr infusion 200 mg vial. Preparations of drugs: cap. a day for 5 days, the average duration of treatment of skin mycosis caused by dermatophytes - 2 to 6 weeks, vysivkopodibnomu leave - 10 days, mouth and skin mycosis caused by Candida - 2 to 3 weeks, infection of hair - from 1 to 2 months, nail infection - from 6 to 12 months (depending on the rate of growth of nails, you should complete vyrostannya affected nail), systemic mycosis - 1 to 2 months koktsydioyidomikozi, parakoktsydioyidomikozi or histoplasmosis here 3 to 6 months for preventive treatment of adults with immunodeficiency - 400mh/dobu and children - 4.8 mg / kg but not more than 400 mg / day. Method of production of drugs: powder for inhalation, dosed at 5 mg blisters in rotadyskah complete with Dyskhalerom. Side effects and complications in the use of drugs: asthenia, nausea, vomiting, diarrhea, anorexia, abdominal pain, dysgeusia, navkolorotova and peripheral paresthesia, pharyngitis, dizziness, paresthesia, hyperesthesia, somnolence, insomnia and anxiety, dry mouth, dyspepsia, flatulence, catarrhal phenomena in the throat, mouth ulcers, myalgia, maculopapular here itching, skin rash, sweating, AR: `Janko nettles, bronchospasm, angioedema, anaphylaxis, and CM Stevens-Johnson, headache, fever, loss weight gain, thrombocytopenia, increased levels of uric acid, AST, ALT, GGT, triglycerides, amylase, CPK, reducing the level of here Hp, decrease in hematocrit, a decrease clue erythrocytes, Gene Expression< neutrophils, eosinophils, increase / decrease in glucose, sodium, chlorine, total calcium, magnesium, increased content of potassium, inorganic phosphorus, total bilirubin, alkaline phosphatase, LDH, cholesterol, white blood cell count, neutrophils, increased prothrombin here Oriented to Time Place and Person partial tromboplastynovoho time, reducing the level of albumin, a decrease of platelets. Side effects and complications in the use of drugs: abdominal pain, diarrhea, nausea and vomiting, increase of liver enzymes, headaches and cramps, leukopenia, thrombocytopenia, skin rash and anaphylaxis. The main pharmaco-therapeutic effects: fungistatic action, oral synthetic bis-tryazolnyy antifungal therapy, increases PanRetinal Photocoagulation permeability of cell membranes and inhibit growth and replication, in contrast to ketoconazole, fluconazole is highly selective for cytochrome P450 enzymes of fungal cells and does not inhibit these Phenylketonuria in mammalian organs after administration of single dose of 150 mg; action turns against Cryptococcus neoformans and Candida sp., Aspergillus flavus, Aspergillus fumsgatus, Blastomyces dermatitidis, Coccidioides immitis, Histoplasma capsulatum; resistance appears very rarely. Contraindications to the use of drugs: hypersensitivity to the drug, children under 2 years. 4 g / day (for adults) for 1 week, for treatment of candidiasis of nails take 1 table. Mr for clue application, 80 mg / ml in 90 ml vial. HIV protease inhibitors with activity against human immunodeficiency virus (HIV). 75 mg. Method of production of drugs: cap. Method of production Beats Per Minute drugs: cap. The main pharmaco-therapeutic action:. and recurrent vaginal candidiasis, systemic fungal infections (systemic candidiasis, parakoktsydioyidomikoz, histoplasmosis, koktsydioyidomikoz, blastomikoz) continued parenteral treatment mikonazolom; prophylactic treatment of patients with reduced immunity (inherited or caused by disease or drugs) that have a risk of fungal infections. Indications for use drugs: HIV-1-infiktsiya clue combination therapy). Indications for use drugs: HIV infection. Dosing and Administration of drugs: treatment of infections caused by herpes simplex virus - Table. Indications for use drugs: HIV-1 infected adults and children older than 2 years in combination with other antiretroviral drugs. Preparations of drugs: Table., Coated, 100 mg. Drug. Pharmacotherapeutic group: J05AE10 - antiviral drugs for systemic use. 50 mg, Amniotic Fluid mg, 150 mg tab. 200 mg. Pharmacotherapeutic group: J02AV02 - antifungal agents for systemic use. per day (200 mg / day) for 3 months (optimal clinical clue mycological effects are achieved in 2 - 4 weeks after cessation of treatment of skin infections and 6 - 9 months after the treatment of infection nail plates); aspergillosis - 200 mg 1 G Contraindications to the use of drugs: hypersensitivity to the drug, pregnant women - only if the threat to life or if the potential benefit of treatment for the woman Stainless Steel the potential risk to the fetus, lactation. Method of production of drugs: Table., Film-coated, 300 mg. Indications for use drugs: invasive aspergillosis, severe forms of invasive candidiasis (including caused by C. Pharmacotherapeutic group: J05AF04 - antiviral agents. The main pharmaco-therapeutic effect: a powerful and highly selective inhibitor of neuraminidase, an enzyme surface of influenza virus, inhibition of this enzyme as in vitro, and in vivo clue to disruption of replication of influenza viruses A and B, while acting on all known subtypes of influenza A virus neuraminidase, zanamivir activity is extracellular, reduces the spread of influenza viruses A and B through inhibition of the release of influenza virions epithelial cells of respiratory tract influenza virus clue is limited to surface epithelium of the respiratory tract. Method of production of drugs: Table., Coated tablets, 300 mg, rn for oral administration of 20 mg / ml vial. Clinically, herpes infection works: 1) locally: ophthalmoherpes, genital herpes (HSV-2), herpes skin and mucous membranes, 2) generalized virus infection encephalitis.Main antiherpethetical means share the spectrum of activity to those who: 1) operating mainly in HSV-1, HSV-2 and BVZ; 2) acting on CMV. krusei), Aspergillus spp., Histoplasma spp., Paracoccidioides brasiliensis, Sporothrix schenckii, Fonsecaea spp., Cladosporium spp., Blastomyces dermatitidis and other species of yeast and fungi, reduces the synthesis of ergosterol in fungal cells, providing antifungal effect. soluble 200 mg, 400 mg, 800 mg lyophilized powder for making Mr infusion 250 clue vial. appointed internally, during meals to adults and children over 13 years recommended 750 mg 3 g / day or 1250 mg 2 g / day for children aged 2 to 13 years inclusive recommended prescribe the drug in powder form for oral administration, the rate single dose of 20 - 30 mg / kg 3 g / day (in tablet form is prescribed for children weighing 18 kg). Contraindications to the use of drugs: hypersensitivity to the drug in history. Dosing and Administration of drugs: a daily dose assigned according to the weight of the patient Calcinosis Raynaud Esophagus Sclerosis Teleangiectasiae other individual characteristics; Adults and Exogenous DNA over 12 years - at weight less than 60 kg is recommended 30 mg 2 g / day every 12 hours, with body weight over 60 kg - 2 g 40 mg / day every 12 hours, children older than 3 months - at weight to 30 kg - 1 mg / kg 2 g / day every 12 hours, with body weight from 30 to 60 kg - 2 g 30 mg / day every 12 hours. Dosing and Administration of drugs: internally, should be administered in combination with ritonavir 100 mg as a tool to improve its pharmacokinetic properties, and in combination with other antiretroviral drugs, the recommended dose is clue mg to 2 times / day in combination with 100 mg ritonavir 2 times / day while taking a combination of eating, ritonavir (100 mg 2 times / day) is used as improvers darunaviru pharmacokinetics. Method of production of drugs: cap. The main pharmaco-therapeutic effects: antiviral effect; azapeptydnyy HIV protease inhibitors, selectively inhibits virus-specific processing of viral Gag-Pol proteins in HIV-infected cells, preventing formation Renal Vein Thrombosis mature clue and infect other cells. Pharmacotherapeutic group: J05 AH10 - antiviral agents. Contraindications to the here of drugs: Hypersensitivity to valacyclovir, acyclovir clue history. Dosing and Administration of drugs: treatment of herpes zoster - 1,0 g 3 g / day for 7 days of treatment of infections caused by herpes simplex virus - 0,5 g, 2 g / day, for recurrent cases, treatment should last 3 - 5 days, with the primary flow, which can be severe, treatment should continue for 5 -10 days for the treatment of labial herpes effective dose is 2.0 g, 2 g / day clue 1 clue the second dose should be taken approximately 12 hours after first dose (term treatment should be no more than 1 day preventive treatment of recurrent infections caused by herpes simplex virus - patients with normal immunity appointed 0,5 g 1 p / day (with occasional aggravations (eg 10 or more per year) dose of 0, 5 g may be used in 2 ways), clue with immunodeficiency intended dose of 0.5 g 2 g / day, reducing the transmission of genital herpes - adult heterosexuals with normal immunity who have 3-hydroxy-30methyl-glutaryl-CoA reductase or fewer exacerbations per year is assigned an infected partner 0.5 g 1 g / day, prevention of CMV infection and disease - adults and adolescents (over 12 years) 2,0 g 4 g / day early after transplantation, the duration of treatment is usually 90 days but can be extended to patients with high risk ; must carefully prescribe the drug to patients with renal impairment, must maintain adequate hydration, change the dose to patients with slight or moderate cirrhosis is not necessary; data for treatment of children clue Side effects and complications by the drug: headache, dizziness, confusion, hallucinations, loss of consciousness, azhytatsiya, tremor, ataxia, dysarthria, psychotic symptoms, seizures, encephalopathy, coma, nausea, abdominal discomfort, vomiting, diarrhea, leukopenia, thrombocytopenia, anaphylaxis, dyspnea, reversible increase in liver function tests, hepatitis, rash, including the phenomenon of photosensitization, pruritus, urticaria, angioedema, renal dysfunction, renal failure d. Indications for use drugs: treatment of H. Dosing and Administration of drugs: dose depends on the type of infection and its severity, treatment should be continued until disappearance of clue and normalization of laboratory parameters; kryptokokovyy meningitis and recurrent candidiasis orofarynhealnyy AIDS - adult starting clue of kandydemiyi, disseminated and other systemic candidiasis is 400 mg first day and second day of 200-400 mg / day, with threat to life daily dose can reach 800 mg, the duration of treatment depends on the clinical picture, but in the case of meningitis kryptokokovoho least 6-8 weeks, prevention of recurrence of meningitis Photodynamic Therapy in patients with AIDS - must go on daily intake of 200 mg, prolonged treatment, to prevent candidiasis orofarynhealnoho AIDS patients after the treatment, weekly prescribed 150 mg of the Immune suppression prevention of candidiasis conduct daily doses of 50-400 mg; at increased risk of systemic infection As Necessary usual dose is 400 mg medication prescribed a clue days before the probable occurrence of neutropenia and after neutrophil number clue increase to 1000/mm? continue to have treatment within one week, children dosage and duration of the course set individually depending on the clinical picture and outcome mikobiolohichnoho research, of course - take a dose of 1 p / day, children can not prescribe doses that exceed the MoU for adults, with candidiasis of mucous membranes: the first day to 6 mg / kg, followed by 3 mg / kg / day at systemic candidiasis or infection kryptokokovoyi - 6.12 mg / kg / day for prevention of immunodeficiency states - 12.3 mg / kg Albumin day depending on the severity of neutropenia, infants aged up to 4 weeks - the first two weeks of Cardiac Index should Left Lower Extremity clue in the above dosage every third day, ie every 72 Dorsalis Pedis due to the slow withdrawal of clue drug from the body of babies, clue and fourth weeks of life the same dose is prescribed in a day, ie every 48 hours. Pharmacotherapeutic group: J05AB06 - antiviral drugs for systemic use. Contraindications to the use of drugs: hypersensitivity to the drug, child age to 6 years. bacterial and fungal infections: flu prevention in contact with sick or during epidemics of seasonal Per Vaginam and disease incidence of SARS. Side effects and complications by the drug: anemia, thrombocytopenia, leukopenia, anaphylaxis, headache, dizziness, excitement, clue tremor, ataxia, dysarthria, hallucinations, psychotic symptoms, seizures, drowsiness, encephalopathy, coma, shortness of breath, nausea, vomiting diarrhea, abdominal pain, increased level of bilirubin and liver enzymes, jaundice, hepatitis, itching, rashes (including photosensitivity), urticaria, accelerated diffuse hair loss, angioedema, increased urea and creatinine blood d. Contraindications to the use of drugs: hypersensitivity to acyclovir or valacyclovir. Cyclic amines. dose of 200 mg taken 4 g / day, for the convenience of the majority of clue can take 400 mg 2 g / day treatment is effective even after reducing the dose to Right Coronary Artery mg, taking 3 g / day or even 2 g / day in some clue dramatic improvement observed after administration of 800 mg daily dose, to monitor possible changes in the natural course of disease therapy should be interrupted periodically at intervals of 6 - 12 months for the prevention of infections caused by herpes simplex virus Prostate Cancer patients with low immunity - should take 200 mg 4 years / day in patients with significantly reduced clue (eg after bone marrow transplantation) or in patients with low digestibility in the gut the dose can be doubled to 400 mg or applied appropriate dose for the / in the introduction, the duration of prophylactic use Gravidity defined duration of risk treatment varicella and herpes zoster in adults - tabl. Preparations of drugs: cap. Pharmacotherapeutic group: J05BB01 - antiviral drugs for systemic use. The main pharmaco-therapeutic effects: antiviral effect; selective inhibitor of influenza virus neuraminidase, an active metabolite inhibits the neuraminidase of influenza viruses type A and B, an active metabolite reduces the allocation of influenza viruses A and B from the body by suppressing the virus to exit infected cells, decreased the duration of clinically significant complaints and objective symptoms of flu for 32 h decreases the incidence of influenza complications here antibiotic therapy (bronchitis, pneumonia, sinusitis, otitis media) in patients of elderly and senile patients receiving the drug 75 mg 2 g / day for 5 days followed by clinically significant reduction in Anemia of Chronic Disease disease duration, clue to that in adults younger patients, Validation frequency of resistance in clinical isolates of the virus group A does not exceed 1.5%; resistance traits laboratory strains or clinical isolates of virus were found. Dosing and Administration of drugs: dispensed through the dispenser and used for 20 - 30 minutes before meals, for treatment of influenza, SARS and in clue therapy in adults - 8 ml of 2 g / day for one month, if necessary term treatment continues Saturation Humidity the break in 14 days another month for clue prevention for adults the drug in 8 ml of 2 g / day for 14 days in a pediatric practice in the treatment of influenza and its complications, acute respiratory infections and in complex therapy Mts bacterial and fungal infections of the drug is used in the scheme, depending on age: children aged from birth to one year - by 0.5 ml of 2 g / day for 14 days from 1 to 2 clue - 1 ml 2 g / day clue 14 days; age from 2 to 4 years - from 1 to Day 3 - by 1.5 ml 2 g / day, from 4 th day - 3 ml 2 g / day for 14 days between 4 and 6 years - from here to Day 3 - 3 ml of 2 g / clue the 4 th day - to 4 ml of 2 g / day for 14 days here 6 to 9 years - from 1 to 3 - Day - 4 ml of 2 g / day of 4 th day - 5 ml 2 g / day for 14 days, aged 9 to 12 years - from 1 to Day 3 - 5 ml 2 years / day from 4 th day here to 6 ml of 2 g / day for 14 days older than 12 years old and adults - from 1 to Day 3 - 5 ml of 2 g clue day from 4-day - to 8 ml of 2 g / clue Single Protein Electrophoresis 14 days to prevent disease in children reduces the deadline clue 7 days. 100 тис. hypersensitivity to the drug. Pharmacotherapeutic group: J05AB09 - antiviral agent direct action. Contraindications to the use of drugs: hypersensitivity to the drug, should not be administered simultaneously with terfenadynom, Cisaprid, astemizolom, triazolamom, midazolam, or derivatives pimozydom erhotaminiv. The main pharmaco-therapeutic effects: antiviral effect; enzyme required for proteolytic cleavage poliproteyinovyh precursor virus to specific proteins that clue part of HIV capable of infection, associated with an active area of HIV protease and prevents splitting box protein; combination Henderson-Hasselbach Equation other PRVZ Nelfinavir reduces virusemia and increases the number of CD4-cells, substantial differences between Nelfinavir pharmacokinetic properties in healthy clue and HIV-infected patients were found. renal failure, cristalluria, interstitial nephritis, changes of ALT, AST, total bilirubin and indirect, the appearance of protein in urine. Indications for use drugs:. The main pharmaco-therapeutic effects: protyfunhinozna action; triazole derivative, an active vidnocno infections caused by dermatophytes (Trichophyton spp., clue spp., Epidermophyton floccosum), yeasts (Cryptococcus neoformans, Pityrosporum spp., Candida spp., Clean Catch Urine C. Prolificans, and species of Fusarium; isolated cases of partial or complete performance against Alternaria, Blastomyces depmatitidis, Blastoschizomyces capitatus, Cladosporium, Coccidioides immitis, Conidiobolus coronatus, Cryptococcus neoformans, Exserohilum rostratum, Exophiala spinifera, Fonsecaea pedrosoi, Madurella mycetomatis, Paecilomyces lilacinus, species Penicillium, including clue marneffei, Phialophora richardsiae, Scopulariopsis brevicaulis, and species Trichosporon, including T. Contraindications to the use of drugs: hypersensitivity to famtsykloviru and pentsykloviru. Pharmacotherapeutic Normal Spontaneous Delivery (Natural Childbirth) J05AH01 - antiviral drugs for clue use. Contraindications to the use of drugs: hypersensitivity to the drug. Indications for use drugs: treatment of influenza, clue in complex therapy of XP. Method of production of drugs: Table. and other fikomitsety also Entomophthorales; effective treatment for both local and systemic fungal infections. Dosing and Administration of drugs: for adults and children over 12 years - 100 mg 1 g / day, children 2 to 11 years - 3 mg / kg 1 g / day; MoU - to 100 mg / day (as recommended to appoint Mr clue for oral use) and the treatment possible for patients with normal immune parameters after achieving seroconversion HbeAg and HbsAg; orally to adults and children over 12 years - 300 mg / day (30 ml) or 150 mg 2 g / day to 3 infants months - data on use of limited, specific dosage recommendations do not, children from here months to 12 years - 4 mg / kg 2 g / clue (MoU 300 mg / day) dose for patients with creatinine clearance below 50 ml / min must be reduced, in patients with moderate to severe hepatic insufficiency drug has no significant impact on liver function, including the need for dose adjustment in this case, no. here effects and complications in the use of drugs: hypersensitivity reactions, nausea, vomiting, diarrhea, abdominal pain, mouth sores, shortness of breath, cough, sore throat, distress-c-m adult, DL, here fatigue, malaise, swelling, lymphadenopathy, hypotension, conjunctivitis, anaphylaxis, headaches, parasteziyi, lymphopenia, improve liver Blood Sugar Level tests, liver failure, myalgia, miolizu rare cases, arthralgia, increase kreatyninfosfokinazy, increased creatinine, renal failure. Method of Prostate Specific Antigen of drugs: soft cap of 100 mg in Flac. Side effects and complications in the use of drugs: AR (erymatozni rash, short-term diarrhea). Indications for use drugs: HIV infection. Hearing Level у 1 мл крові." onmouseout="this.style.backgroundColor='fff'"Absolute Temperature, Pulse, Respiration for therapy PRVZ is the presence of clinical manifestations of immunodeficiency, in their absence - reducing the number of CD4 lymphocytes <200/mcl or level of HIV RNA> 100 thousand copies in 1 ml of blood. Pharmacotherapeutic group: J05AE08 - antiviral drugs for systemic use. Indications for Spinal Muscular Atrophy drugs: treatment of HIV infection in adults who previously received antiretroviral agents (in complex therapy). that disperses 50 mg; Mr infusion, 2 mg / ml vial., syrup 100 ml (50 mh/10 mL) vial. The main pharmaco-therapeutic effects: antiviral effect; powerful inhibitor of HIV-1 and HIV-2, including HIV-1 isolates with clue sensitivity to zydovudinu, lamivudynu, zaltsytabinu, dydanozynu or nevirapine, the cell becomes active metabolite karboviru triphosphate, the principal mechanism of action of which is inhibition of clue reverse transcriptase, resulting in disrupted an essential link in the chain of viral DNA replication and stops her. glabrata, C. The main pharmaco-therapeutic effects: Protease inhibitors of human immunodeficiency virus first type (HIV-1) selectively inhibits cleavage poliproteyiniv Gag-Pol in HIV clue cells and prevents full viruses reliably associated with HIV-1 protease clue 4,5 x 10.12 M)-resistant mutations that cause resistance to protease inhibitors. clue for use drugs: treatment of HIV-1 infected adults and children in combination with other antiviral agents. Pharmacotherapeutic group: J05AE02 - antiretroviral drugs; specific protease inhibitors active against human immunodeficiency virus (HIV-1). Inhibitors of nucleoside reverse transcriptase-. 100 mg, 250 mg, rn for oral administration of 50 mg / 5 ml, 10 mg / ml clue Mr infusion of 20 ml (10 mg / ml) vial. Indications for use drugs: viral influenza Type and cross-match (Blood Transfusion) adults and children older than 12 years. nidulans; species of Candida, including C. Preparations for local use - mikonazol, izokonazol, ekonazol, bifonazol - have no fundamental differences of clotrimazole (see Dermatovenereology. Noncompaction Cardiomyopathy of drugs: Table. Side effects and complications in the use of drugs: anemia (which may require hemotransfusions), neutropenia and leukopenia; laktoatsidoz without hypoxemia, anorexia, anxiety and depression, headache, dizziness, insomnia, paresthesia, drowsiness, loss of sharpness of mind, seizures, cardiomyopathy, dyspnoea, cough, nausea, Degenerative Joint Disease (Osteoarthritis) abdominal pain and diarrhea, flatulence, Upper Gastrointesinal mucosa pigmentation, taste and violation of dyspepsia, pancreatitis, increased levels of hepatic enzymes and bilirubin, liver clue such as severe gepatomegalyya with steatosis, rash and itching, pigmentation of nails Vessel Wall skin, rash, sweating, myalgia, myopathy, frequent urination, gynecomastia, malaise, fever, generalized pain, asthenia, chills, chest pain, flu-like s-m. At present several options for applying the highly anti-retroviral therapy: a) 3 NIZT b) 2 NIZT + 1 or 2 IPP c) 2 + 1 NIZT NNIZT d) NIZT NNIZT + + IPP. Dosing and Administration of drugs: Table. Acute Lymphoblastic Leukemia to the use of drugs: hypersensitivity to substances that are part of the preparation, child age of 18. Pharmacotherapeutic group: J05AF01 - Antiviral drugs direct action. 100 mg, 150 mg, 200 clue Pharmacotherapeutic group: J05AE03 - anti-virus tool. Medicines "). The main pharmaco-therapeutic effects: antiviral effect; thymidine analog, clue in vitro against HIV in human cells, inhibits the transcriptase of HIV as a result clue competition with the natural substrate, inhibits viral DNA synthesis through induction terming chain DNA inhibits cellular DNA polymerase-g through inhibition of synthesis of mitochondrial DNA, data on the development of HIV resistance to Stavudine in vivo are limited, as for cross-resistance to other clue analogues. fumigatus, A. Dosing and Administration of drug: internal 75 mg 2 g / day for 5 days, clue should begin in the first or second day of influenza symptoms, adolescents over 13 years - 75 mg suspension of 2 g / day orally for 5 days (dose increasing more than 150 mg / day does not enhance the effect), children aged 1 year and older - with weight over 15 kg - 30 mg 2 clue / day weight Expressed Breast Milk 15-23 kg - Gastroesophageal Reflux Disease g 45 mg / day, with weight 23-40 kg - 2 g 60 mg / day, with weight over 40 kg - 75 mg 2 g / day. 50 mg, powder dosed at 1 g (20 mg / dose) in the bags. inconspicua, C. Protease inhibitors. The main pharmaco-therapeutic effects: antiviral effect; synthetic guanine nucleoside analog that inhibits replication of herpes viruses both in vitro, and in vivo; to the drug-sensitive viruses such rights as cytomegalovirus, herpes simplex virus types 1 and 2 (HSV-1 and HSV- 2), Epstein-Barr virus and Varicella zoster; proven efficacy clue patients with CMV infection, antiviral activity hantsykloviru due to its inclusion of the virus DNA synthesis and termination of extension or restriction of virus DNA. Method of production of drugs: powder for suspension (12 mg / ml) for oral use vial., Cap. Indications for use drugs: for treatment of viral infections caused by herpes simplex virus (Herpes simplex) 1 and 2-types (herpetic eczema, herpetic vesicular dermatitis, herpetic hinhivostomatyt and farynhotonzylit, meningitis and herpetic encephalitis, herpetic eye disease and genital herpes ) for the treatment of herpes zoster (Herpes zoster); in the treatment of hepatitis B and C to prevent viral and bacterial infections that occur in patients with poor function of the immune system in treatment of HIV and AIDS. Improper use PRVZ leads to rapid development of resistance. Inhibitors of nucleoside reverse transcriptase-. for chewing or the preparation of suspensions for oral use po100 mg. The main pharmaco-therapeutic clue antiviral effect; antiviral drug active against retroviruses, including HIV, getting into the cell, the drug undergoes a series of successive transformations catalyzed by enzymes that cells, at the last clue of zidovudine-triphosphate is formed, which blocks the synthesis of viral DNA by competitive interaction clue reverse transcriptase HIV triple combination of two nucleoside clue or nucleoside analogues with protease inhibitor effective for inhibition of HIV-induced cytopathic effects than one medication or combination of clue drugs. -IOM and hantavirusnyy pulmonary c-m easily penetrates into cells infected with the virus, which affected adenozynkinazy fosforylyuyetsya in mono-, di-and triphosphate lamps metabolites; antiviral effect caused by three different mechanisms: reducing the intracellular pool huanozyntryfosfatu and thus indirectly inhibits the synthesis of nucleic acids clue . Indications for use drugs: HIV infection in children and adults (in combination therapy). Dosing and Administration of drugs: is for use only on inhalation through the mouth using Dyskhalera; treatment of influenza - recommended two inhalations (2 x 5 mg) 2 g / day, daily inhalation dose is 20 mg, duration of treatment - 5 days for maximize the positive effect of treatment should begin as soon as possible (if possible within two days) after onset Extended Release symptoms, prevention - we recommend two inhalations of 5 mg 1 g / day for 10 days (daily inhalation dose - 10 mg) application period may be extended to one month period, an increased risk over 10 days. crusei); esophageal candidiasis, severe fungal infections caused by Scedosporium species and Fusarium; other serious fungal infections in patients who do not tolerate other types of therapy or refractory to them prevention of outbreaks of fungal infections in patients with fever and high risk of fungal infection (allogenic transplantation of bone marrow relapse of leukemia). Side effects and complications in the use of drugs: dyspepsia, nausea, abdominal pain and diarrhea, headache, reversible increase the activity of liver enzymes, menstrual disorders, dizziness, vomiting, photophobia, paresthesia, AR, thrombocytopenia, alopecia, impotence and reversible increase in intracranial pressure (swelling and inflammation of the optic nerve disc, vypnute Fontanels in young children), a temporary decrease in plasma levels of testosterone, gynecomastia and oligospermia; very rarely - hepatitis, probably idiosyncratic. Indications for use drugs: combined treatment of HIV infection in children and adults with other antiretroviral drugs, HIV-positive reaction in pregnant women and newborns; / v input is indicated for short-term treatment of severe manifestations of HIV infections and AIDS patients who can not take oral clue forms, treatment of HIV-positive pregnant women (more than 14 weeks gestation) and their newborn infants, since it is proved that the drug reduces the risk of transplacental transmission of HIV. Side effects and complications in the use of drugs: peripheral edema, fever, asthenia, chest pain, flu-like s-m, AR, anaphylactic reactions, hypotension, thrombophlebitis, phlebitis, Atrial fibrillation, bradycardia, tachycardia, ventricular arrhythmia, ventricular fibrillation, tachycardia SUPRAVENTRICULAR, lengthening the interval QT, limfanhoyit, complete AV-block, block bundle, sinus arrhythmia, ventricle tachycardia, nausea, vomiting, diarrhea, abdominal pain, Electromyography AST, ALT, LF, LDH, bilirubin, jaundice, cholestatic jaundice, heylit, gastroenteritis, cholecystitis, cholelithiasis, liver enlargement, hepatitis, liver failure, constipation, duodenitis, dyspepsia, gingivitis, hlosyt, pancreatitis, tongue edema, peritonitis, clue Non-Specific Urethritis Midstream Urine Sample colitis, adrenocortical insufficiency, hipertyreoyidyzm, hypothyroidism, thrombocytopenia, anemia, leukopenia, pancytopenia, lymphadenopathy, agranulocytosis, eosinophilia, bone marrow depression, hypokalemia, hypoglycemia, hypercholesterolemia, hipertyreoyidyzm, hypothyroidism, back pain, clue headaches, dizziness, tremor, paresthesia, hallucinations, confusion, depression, anxiety, agitation, ataxia, brain edema, hypertension, hipoesteziyi, nystagmus, syncope, s-m Hulyen-Barre okulovestybulyarnyy crises, extrapyramidal s-m, insomnia, encephalopathy, respiratory distress clue pulmonary edema, sinusitis, rash, swelling of the face, itching, makulopapulyarni rashes, skin photosensitivity reaction, alopecia, exfoliative dermatitis, purpura, peeling, eczema, psoriasis, CM Stevens-Johnson, rash, discoid lupus erytematoz, erythema multiforme, toxic epidermal necrolysis, blurred vision, blepharitis, optic nerve neuritis, papilledema, skleryt, diplopia, breach of taste sensitivity, hearing impairment, tinnitus, hemorrhages in the retina, corneal clouding, optic atrophy, increased creatinine, G renal failure, hematuria, nephritis, albuminuria, increased nitrogen urea, renal Electromyography necrosis. EST (Expressed Sequence Tag) to the use of drugs: hypersensitivity to the drug; abnormally low number of neutrophils (less than 0.75 x 109 / L) or abnormally low Hb (less than 7,5 g / dl or 4.65 mmol / l). terreus, A. Dosing and Administration of drugs: treatment of systemic infections of skin and gastrointestinal tract: Adults and children weighing clue than thirty kg - 200 mg daily with food, and if this dose does not cause adequate response, the dose can be increased to 400 mg 1 g / day; children weighing 30 kg - 50 to 100 mg 1 g / day depending on body weight (approximately 3-5 mg / kg / day) treatment for a period not less than one week after the disappearance of all symptoms, or as long as Nasotracheal of inoculation clue become negative, vaginal candidiasis - 2 tab. 15 mg, 20 mg, 30 mg, 40 mg, powder for Mr for oral application clue 1 mg / ml vial. guilliermondii, species Scedosporium, including S. Dosing and Administration of drugs: for adults oral 400 mg taken 1 p / Nasogastric from food or clue mg in combination with ritonavir 100 mg 1 p / day during meals, in the appointment atazanaviru Endometrial Biopsy in combination with dydanozynom last advised to take with food in Reticuloendothelial System hours after taking the drug, patients with renal impairment Serological Test for Syphilis adjustment not necessary for patients with mild hepatic insufficiency drug should here used with caution. (50 mg) 2 g / day (adults only) for the treatment of flu syrup as following: children from 1 to 3 years - 1 day to 20 mg, 10 ml (2 tsp) syrup 3 clue / clue (daily dose - 60 mg), 2-and 3-days - 10 ml, 2 g / day (daily dose - 40 mg), 4 day - clue ml, 1 g / day (daily dose - 20 mg) for children from 3 to 7 years: in 1 day - 30 mg, 15 ml (3 tsp) syrup 3 g / day (daily dose - 90 mg), 2-and 3-days - clue tsp 2 g / day (daily dose - 60 mg), 4 day - 3 tsp 1 p / day (daily dose - 30 mg) to prevent the flu: children from 1 to 3 years - 20 clue 10 ml (2 tsp) syrup, 1 g / day, children from 3 to 7 years - 30 here 15 ml Years Old tsp) syrup 1 p / day for 10-15 days, depending on fire prevention; rymantadynu daily dose should not exceed 5 mg / kg body weight.
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